Occupancy Modeling, Maximum Contig Size Probabilities and Designing Metagenomics Experiments

@inproceedings{Stanhope2010OccupancyMM,
  title={Occupancy Modeling, Maximum Contig Size Probabilities and Designing Metagenomics Experiments},
  author={Stephen A. Stanhope},
  booktitle={PloS one},
  year={2010}
}
Mathematical aspects of coverage and gaps in genome assembly have received substantial attention by bioinformaticians. Typical problems under consideration suppose that reads can be experimentally obtained from a single genome and that the number of reads will be set to cover a large percentage of that genome at a desired depth. In metagenomics experiments genomes from multiple species are simultaneously analyzed and obtaining large numbers of reads per genome is unlikely. We propose the… CONTINUE READING

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