Occult lifelong persistence of infectious hepadnavirus and residual liver inflammation in woodchucks convalescent from acute viral hepatitis.

@article{Michalak1999OccultLP,
  title={Occult lifelong persistence of infectious hepadnavirus and residual liver inflammation in woodchucks convalescent from acute viral hepatitis.},
  author={Tomasz I. Michalak and Ingrid Pardoe and Carla S Coffin and Norma D. Churchill and Debbie Freake and Paula Smith and C L Trelegan},
  journal={Hepatology},
  year={1999},
  volume={29 3},
  pages={928-38}
}
Traces of hepatitis B virus (HBV) genome can persist for years following recovery from hepatitis B. To determine overall duration, molecular characteristics, and pathological implications of this serologically undetectable form of hepadnaviral carriage, we have analyzed the expression of transcriptionally active virus genomes, their infectivity, and examined liver alterations during the natural lifespan of woodchucks convalescent from acute infection with HBV- related woodchuck hepatitis virus… CONTINUE READING
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