Occult hepatitis B virus infection: detection and significance.

@article{Gerlich2010OccultHB,
  title={Occult hepatitis B virus infection: detection and significance.},
  author={Wolfram H. Gerlich and Corinna M. Bremer and Mona Saniewski and Christian G. Sch{\"u}ttler and Ulrike C. Wend and Wulf R Willems and Dieter Glebe},
  journal={Digestive diseases},
  year={2010},
  volume={28 1},
  pages={116-25}
}
The Taormina Consensus Conference defined 'occult hepatitis B virus (HBV) infection' (OBI) as the 'presence of HBV DNA in the liver of individuals testing HBsAg-negative with currently available assays'. Most occult is the so-called 'window period' after exposure before HBV DNA appears in the blood. We identified two blood donors whose donations tested HBsAg- and HBV DNA-negative, but transmitted HBV. Both subsequently developed HBsAg and acute hepatitis. However, such cases are not considered… CONTINUE READING

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