Obstructive sleep apnoea syndrome impairs insulin sensitivity independently of anthropometric variables.

@article{Tassone2003ObstructiveSA,
  title={Obstructive sleep apnoea syndrome impairs insulin sensitivity independently of anthropometric variables.},
  author={Francesco Tassone and Fabio Lanfranco and L. Gianotti and Sonia Pivetti and Fabrizia Navone and Ruth Rossetto and Silvia Grottoli and Valerio Gai and Ezio Ghigo and Mauro Maccario},
  journal={Clinical endocrinology},
  year={2003},
  volume={59 3},
  pages={374-9}
}
OBJECTIVES Obstructive sleep apnoea syndrome (OSAS) is strongly associated with obesity and characterized by endocrine and metabolic changes including impairment of insulin sensitivity. The aim of this study was to further clarify the insulin dynamics and glucose metabolism in this condition. DESIGN, PATIENTS AND MEASUREMENTS We studied 30 obese patients with OSAS [OSA, 21 males, 9 females; age, mean +/- SEM: 53.1 +/- 1.7 years; body mass index (BMI): 38.6 +/- 1.1 kg/m2; waist-to-hip ratio… CONTINUE READING