Obstructive Jaundice Caused by Non-Hodgkin Lymphoma in Common Bile Duct.


A 45-month-old girl was admitted with a 1-week history of jaundice. Other than the visible jaundice, her physical examination results were normal. Laboratory investigation revealed a total bilirubin level of 8.9 mg/ dL, direct bilirubin level of 7.3 mg/dL. Abdominal ultrasonography revealed a hypoechoic, homogeneous mass in the pancreaticoduodenal region, associated with dilatation of the extra-hepatic bile ducts. Computed tomography confirmed these findings, but failed to distinguish the margin between the mass, pancreatic head, distal common bile duct, and duodenum (Figure 1; available at www.jpeds.com). Laparotomy revealed the region of the hepatoduodenal ligament and that the pancreatic head was thickened and immobilized. A fish flesh-like tumor was observed in the common bile duct (Figure 2). Pathologic diagnosis was anaplastic large cell lymphoma (ALCL), anaplastic lymphoma kinase positive. Biopsy tissues taken from the gallbladder, hepatoduodenal ligament, and pancreatic head were free of tumor invasion. ALCL comprises approximately 15% of all non-Hodgkin lym-

DOI: 10.1016/j.jpeds.2015.08.019

Cite this paper

@article{Yang2015ObstructiveJC, title={Obstructive Jaundice Caused by Non-Hodgkin Lymphoma in Common Bile Duct.}, author={Tianyou Yang and Jing Pan and Yan Zou}, journal={The Journal of pediatrics}, year={2015}, volume={167 5}, pages={1168-8.e1} }