Obstacles to ideal anti-HIV antibody-dependent cellular cytotoxicity responses.


A safe and effective vaccine against HIV is a global health priority. Large-scale phase III clinical vaccine trials based on neutralizing antibodies and cytotoxic T-lymphocytes have failed to provide protection, highlighting the lack of understanding of basic immune correlates of protection against HIV. The partial success of the RV144 vaccine trial… (More)
DOI: 10.1016/j.vaccine.2013.08.035


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