Obsessive–compulsive disorder in chronic epilepsy

  title={Obsessive–compulsive disorder in chronic epilepsy},
  author={Peter W. Kaplan},
  journal={Epilepsy \& Behavior},
  • P. Kaplan
  • Published 2011
  • Medicine, Psychology
  • Epilepsy & Behavior
There is a long-recognized association between obsessive-compulsive disorder (OCD) and chronic epilepsy, most notably refractory temporal lobe epilepsy (TLE). The literature documents this association with case reports, patient series, and some larger controlled studies that reveal that almost a quarter of patients with TLE exhibit OCD features, which may go unrecognized. Obsession features with ordering, symmetry, exactness, handwashing, and religiosity occur more often in persons with right… Expand
Crossed obsessive-compulsive personality disorder and impaired theory of mind in temporal lobe epilepsy
A selective association of a Theory of Mind dysfunction, including an impaired comparison of reality and others’ behavior, with an obsessive-compulsive personality disorder in a patient with left temporal lobe epilepsy and crossed cognitive functions is illustrated. Expand
Factors associated with obsessive–compulsive symptoms in people with epilepsy
Obsessive-compulsive symptoms are common in persons with epilepsy and are associated with severe epilepsy, temporal lobe seizures, and the use of topiramate and lamotrigine, which may aggravate OCS and have beneficial effects on OCS. Expand
Differences in obsessive–compulsive symptom dimensions between patients with epilepsy with obsessive–compulsive symptoms and patients with OCD
It was found that patients with epilepsy with OCS tend to have more symmetry/exactness obsessions and compulsions, whereas patients with OCD had significantly more contamination/cleaning and aggressiveness Obsessive-compulsive symptoms. Expand
Neuroimaging and neuropsychological findings in pediatric obsessive-compulsive disorder: a review an
In examining pediatric OCD, neuropsychological performance may serve as a bridge between brain functioning and the phenomenology of the disorder, highlighting both the neural and cognitive developmental processes within the pediatric population. Expand
Structural Brain MR Imaging Changes Associated with Obsessive-Compulsive Disorder in Patients with Multiple Sclerosis
This study suggests that OCD in MS may be caused by damage in the right frontotemporal cortex. Expand
ORIGINAL RESEARCH Structural Brain MR Imaging Changes Associated with Obsessive-Compulsive Disorder in Patients with Multiple Sclerosis
BACKGROUND AND PURPOSE: Psychiatric symptoms occur in approximately 30% of patients with MS. Such symptoms include OCD, which may interfere heavily with the patient’s daily life. We hypothesized thatExpand
[Symptoms of obsessive-compulsive disorder in neurological diseases].
  • M. Kutlubaev
  • Medicine
  • Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova
  • 2016
Signs and symptoms of OCD could develop as a sign of focal brain lesion, particularly in multiple sclerosis, extrapyramidal disorders, epilepsy, less frequently - in other diseases. Expand
The crossroads of anxiety: distinct neurophysiological maps for different symptomatic groups
The findings support diffuse cortical instability in AD in general, with individual differences in information processing deficits and regional hyperactivities in OCD and PD. Expand
Fantastic confabulation in right frontal lobe epilepsy
Fantastic confabulations are rare but may be a relatively specific behavioral marker for FLE-associated psychosis. Expand
Electrical stimulation in the bed nucleus of the stria terminalis alleviates severe obsessive-compulsive disorder
It is found that electrical stimulation in the ALIC/BST area is safe and significantly decreases obsessions, compulsions, and associated anxiety and depressive symptoms, and improves global functioning in a blinded crossover trial, and at last follow-up. Expand


Obsessionality, obsessive–compulsive disorder, and temporal lobe epilepsy
Patients with TLE and OCD differed significantly with respect to history of depression when compared with patients with Tle without OCD, whereas there were no differences in age at onset and duration of epilepsy, seizure pattern and frequency, MRI features, laterality of the EEG focus, antiepileptic drug therapy and combinations, and BDI scores. Expand
A comparative study of obsessive–compulsive disorder and other psychiatric comorbidities in patients with temporal lobe epilepsy and idiopathic generalized epilepsy
Higher comorbidity in TLE suggests that involvement of the temporal lobe may play a role in the development of specific psychopathological syndromes. Expand
Obsessive–compulsive disorder after epilepsy surgery
This is the first report of OCD after ES in patients with mesial temporal lobe epilepsy (MTLE) and shows that those patients with obsessive traits preoperatively should be carefully monitored after ES. Expand
New-onset obsessive–compulsive disorder following neurosurgery for medication-refractory seizure disorder
The present case is only the fourth reported of de novo onset OCD following neurosurgery for seizure disorder, and the first in a patient without either preexisting obsessive traits or an OCD spectrum disorder. Expand
Late-onset obsessive compulsive disorder associated with possible gliomatosis cerebri
The current patient had obsessive images, anxiety, auditory hallucinations and seizures following (possible) gliomatosis cerebri, with onset around 69 years of age, and the need for careful screening of older patients with recently acquired OCD is illustrated. Expand
Obsessive–compulsive symptoms in patients with temporal lobe epilepsy
As a group, patients with TLE had a higher prevalence of OC symptoms than the nonpatient normative sample, and TLE patients exhibited elevated scores on all but 3 of the 16 OCI scales and subscales. Expand
Obsessive-compulsive disorder associated with brain lesions
The results suggest that acquired and idiopathic OCDs may share a common pathophysiologic mechanism, and that structural damage to specific frontal-limbic-subcortical circuits plays an important role in the pathogenesis of acquired OCD. Expand
Childhood obsessive-compulsive disorder and cingulate epilepsy
The behavioral, cognitive, and EEG findings in a young girl with medically resistant seizures and severe obsessive-compulsive symptomatology are reported, finding a focal seizure origin in the right anterior cingulate gyrus. Expand
Neurological factors in obsessive compulsive disorder. Two case reports and a review of the literature.
  • P. Kettl, I. Marks
  • Psychology, Medicine
  • The British journal of psychiatry : the journal of mental science
  • 1986
It is concluded that neurological factors are present in only a minority of cases of OCD, and successful behavioural treatment is independent of such factors. Expand
A psychological and neuroanatomical model of obsessive-compulsive disorder.
  • E. Huey, R. Zahn, +4 authors J. Grafman
  • Psychology, Medicine
  • The Journal of neuropsychiatry and clinical neurosciences
  • 2008
The authors believe that this model explains the specific symptoms of OCD, and integrates the psychology and neuroanatomy of OCD better than previous models. Expand