Obsessive–Compulsive Disorder: Treatment and Treatment Resistance

@article{Hood2001ObsessiveCompulsiveDT,
  title={Obsessive–Compulsive Disorder: Treatment and Treatment Resistance},
  author={Sean D. Hood and Deirdre Alderton and David Jonathan Castle},
  journal={Australasian Psychiatry},
  year={2001},
  volume={9},
  pages={118 - 127}
}
Objective: To review the treatment options for obsessive–compulsive disorder (OCD), with particular reference to treatment resistance, and provide a guideline for clinicians managing these patients, drawing upon evidence from clinical trials and expert consensus. Conclusions: The behavioural technique of exposure and ritual prevention (EX/RP) and serotonergic medications have emerged as effective standard treatments of OCD, although full symptom remission is rare. Predictors of poor and partial… 

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References

SHOWING 1-10 OF 49 REFERENCES

Effectiveness of psychological and pharmacological treatments for obsessive-compulsive disorder: a quantitative review.

  • J. Abramowitz
  • Psychology
    Journal of consulting and clinical psychology
  • 1997
Quantitative review of the controlled treatment outcome literature for obsessive-compulsive disorder (OCD) showed that exposure with response prevention was highly effective in reducing OCD symptoms.

Cognitive Therapy of Obsessive – compulsive Disorder: Treating Treatment Failures

It is argued that cognitive–behavioural interventions such as the one described here may be useful as an adjunct to more traditional behavioural treatments for obsessional disorders as well as in the treatment of patients with overvalued ideation.

Effectiveness of exposure and ritual prevention for obsessive-compulsive disorder: randomized compared with nonrandomized samples.

Clinical patients achieved substantial and clinically meaningful reductions in their OCD and depressive symptoms following EX/RP, which were comparable with those reported in the RCTs.

The comparative effectiveness of treatments for obsessive-compulsive disorder.

  • J. Greist
  • Psychology, Medicine
    Bulletin of the Menninger Clinic
  • 1998
The comparative efficacies of pharmacotherapy and behavior therapy remain in dispute, although all meta-analyses have identified behavior therapy as more effective both in terms of magnitude of improvement short term and lasting gains long term.

Organicity in Obsessive-Compulsive Disorder

The OCD clinical profile that is correlated to organicity is described and reasons for lack of response in organic OCD patients, based on cerebral anatomical changes, are discussed.

Predictors of drug treatment response in obsessive-compulsive disorder.

There are distinct types of OCD with respect to drug treatment response, which provide indirect evidence of treatment specificity by identifying characteristics responsive to different modalities, which may be of value in the selection of patients for alternative treatments.

Out–patient, multimodal behaviour therapy for obsessive–compulsive disorder

  • I. Hand
  • Medicine, Psychology
    British Journal of Psychiatry
  • 1998
For major subgroups of OCD, behaviour therapy is a very effective treatment modality, but additional interventions are equally important in about half of the patients from unselected samples.

Obsessive-Compulsive Disorder

Optimal results in the management of OCD are often realised through a combination of ERP and pharmacological therapy, although the availability of behavioural therapy is limited.

What predicts improvement and compliance during the behavioral treatment of obsessive compulsive disorder?

Clinical improvement was associated with never having been treated previously, being employed during treatment, having a fear of contamination, having overt ritualistic behaviour, the absence of depression and living with one's family.