Observing single biomolecules at work with the atomic force microscope

@article{Engel2000ObservingSB,
  title={Observing single biomolecules at work with the atomic force microscope},
  author={Andreas Engel and Daniel J M{\"u}ller},
  journal={Nature Structural Biology},
  year={2000},
  volume={7},
  pages={715-718}
}
Progress in the application of the atomic force microscope (AFM) to imaging and manipulating biomolecules is the result of improved instrumentation, sample preparation methods and image acquisition conditions. Biological membranes can be imaged in their native state at a lateral resolution of 0.5–1 nm and a vertical resolution of 0.1–0.2 nm. Conformational… CONTINUE READING