Observations with the Electron Microscope on the Solvation and Reconstitution of Collagen

@article{Vanamee1951ObservationsWT,
  title={Observations with the Electron Microscope on the Solvation and Reconstitution of Collagen},
  author={Parker Vanamee and Keith R. Porter},
  journal={The Journal of Experimental Medicine},
  year={1951},
  volume={94},
  pages={255 - 268}
}
The course of events in the solvation and reconstitution of collagen obtained from rat tail tendon is described as seen with the electron microscope. Under the influence of 0.01 per cent acetic acid the collagen fibers swell and dissociate into submicroscopic filaments, the smallest of which are probably beyond the resolution of the electron microscope. These filaments can be made to reconstitute into fibers either by the addition of neutral salts to the acid solution or by raising the pH. The… CONTINUE READING