Observations on the "cytoskeleton" of human platelets.

  title={Observations on the "cytoskeleton" of human platelets.},
  author={Vivianne T. Nachmias and J S Sullender and Justin R. Fallon and A U Asch},
  journal={Thrombosis and haemostasis},
  volume={42 5},
Structural study of rapidly lysed platelets supports the view that that shape change involves a change in state of the microfilaments which contain actin. The microtubule "bundle" appears to be a continuous coil. Proteolysis of a high molecular weight band is observed in platelets which can no longer form filopodia after suppression by local anesthetics.