Observations of synaptic structures: origins of the neuron doctrine and its current status.

@article{Guillery2004ObservationsOS,
  title={Observations of synaptic structures: origins of the neuron doctrine and its current status.},
  author={Ray W. Guillery},
  journal={Philosophical transactions of the Royal Society of London. Series B, Biological sciences},
  year={2004},
  volume={360 1458},
  pages={
          1281-307
        }
}
The neuron doctrine represents nerve cells as polarized structures that contact each other at specialized (synaptic) junctions and form the developmental, functional, structural and trophic units of nervous systems. The doctrine provided a powerful analytical tool in the past, but is now seldom used in educating neuroscientists. Early observations of, and speculations about, sites of neuronal communication, which were made in the early 1860s, almost 30 years before the neuron doctrine was… CONTINUE READING
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