Observation of Parkin-Mediated Mitophagy in Pancreatic β-Cells.


Mitophagy is a cellular process of autophagy-based mitochondrial degradation that eliminates dysfunctional mitochondria and ensures cellular homeostasis. In pancreatic islet β-cells, mitochondria play a pivotal role in glucose-stimulated insulin secretion through ATP production from glucose oxidation. Recent studies have shown that impaired mitophagy and… (More)
DOI: 10.1007/7651_2017_39


Cite this paper

@article{Hoshino2017ObservationOP, title={Observation of Parkin-Mediated Mitophagy in Pancreatic β-Cells.}, author={Atsushi Hoshino and Satoaki Matoba}, journal={Methods in molecular biology}, year={2017} }