Obligatory role of gamma interferon for host survival in a murine model of infection with Burkholderia pseudomallei.

@article{Santanirand1999ObligatoryRO,
  title={Obligatory role of gamma interferon for host survival in a murine model of infection with Burkholderia pseudomallei.},
  author={Pitak Santanirand and Vicki Harley and David A B Dance and Bohumil S. Drasar and Gregory J Bancroft},
  journal={Infection and immunity},
  year={1999},
  volume={67 7},
  pages={3593-600}
}
Burkholderia pseudomallei, the causative agent of melioidosis, is a gram-negative bacterium capable of causing either acute lethal sepsis or chronic but eventually fatal disease in infected individuals. However, despite the clinical importance of this infection in areas where it is endemic, there is essentially no information on the mechanisms of protective immunity to the bacterium. We describe here a murine model of either acute or chronic infection with B. pseudomallei in Taylor Outbred (TO… CONTINUE READING
85 Citations
38 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 85 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 38 references

Differential effects of granulocyte/macrophage colony-stimulating factor (GM-CSF) in enhancing macrophage resistance to Legionella pneumophilia vs. Candida albicans

  • Y. Yamamoto, T. M. Klein, M. Tomioko, H. Friedman
  • Cell. Immunol. 176:75–81
  • 1997
1 Excerpt

Similar Papers

Loading similar papers…