Objective measurement of surfactant irritation by fiber optic spectroscopy.

@article{Crowe1988ObjectiveMO,
  title={Objective measurement of surfactant irritation by fiber optic spectroscopy.},
  author={D M Crowe and M S Willard and Richard I. Murahata and L B Aust and M C Gacula},
  journal={Contact dermatitis},
  year={1988},
  volume={19 3},
  pages={192-4}
}
Erythema caused by occlusion of 3 concentrations of surfactant was quantified in vivo using a modified spectrophotometer. Standard chamber irritation test sites were evaluated objectively using the spectrophotometer and subjectively by trained observers. There was a good relationship between the instrumental and visual evaluations. The spectrum was analyzed… CONTINUE READING