Objective biologic parameters and their clinical relevance in assessing salivary gland neoplasms.

@article{Pinto2000ObjectiveBP,
  title={Objective biologic parameters and their clinical relevance in assessing salivary gland neoplasms.},
  author={Ant{\'o}nio Evaristo Pinto and Isabel Barahona da Fonseca and Carmo Martins and Jorge Fernando Maxnuck Soares},
  journal={Advances in anatomic pathology},
  year={2000},
  volume={7 5},
  pages={294-306}
}
This review summarizes research advances of cytometric, proliferation, cytogenetic, and molecular "objective" measurable parameters, as additional aids to prognostic information of salivary gland tumors provided by classical clinicopathologic indicators. Flow cytometric DNA ploidy and S-phase fraction seem to be of value as predictors of tumor behavior, aneuploidy, and high S-phase identifying an unfavorable clinical evolution of salivary gland neoplasms. Cell proliferation markers assessed by… CONTINUE READING

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