Objective and subjective impairment from often-used sedative/analgesic combinations in ambulatory surgery, using alcohol as a benchmark.

@article{Thapar1995ObjectiveAS,
  title={Objective and subjective impairment from often-used sedative/analgesic combinations in ambulatory surgery, using alcohol as a benchmark.},
  author={Pinky Manoharlal Thapar and J P Zacny and M Choi and Jeffrey L. Apfelbaum},
  journal={Anesthesia and analgesia},
  year={1995},
  volume={80 6},
  pages={1092-8}
}
Impairment caused by different sedative/analgesic combinations commonly used in ambulatory settings was compared to that of alcohol at blood alcohol concentrations (BACs) higher than or equal to 0.10%. Impairment was measured via subjective (mood) and objective (psychomotor performance) assays. Twelve healthy human volunteers (10 males and 2 females; age range 21-34 yr) participated in this prospective, double-blind, randomized, cross-over study. Each subject was exposed to five drug conditions… CONTINUE READING

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