Object recognition impairment in Fmr1 knockout mice is reversed by amphetamine: involvement of dopamine in the medial prefrontal cortex.

@article{Ventura2004ObjectRI,
  title={Object recognition impairment in Fmr1 knockout mice is reversed by amphetamine: involvement of dopamine in the medial prefrontal cortex.},
  author={Rossella Ventura and Tiziana Pascucci and Maurizio Palesi Vincenzo Catania Univerist{\`a} di Catania and Sebastiano Antonino Musumeci and Stefano Puglisi-Allegra},
  journal={Behavioural pharmacology},
  year={2004},
  volume={15 5-6},
  pages={433-42}
}
Fragile X syndrome is an X-linked form of mental retardation including, among others, symptoms such as stereotypic behaviour, hyperactivity, hyperarousal, and cognitive deficits. We hypothesized that hyperactivity and/or compromised attentional, cognitive functions may lead to impaired performance in cognitive tasks in Fmr1 knockout mice, the most widely used animal model of fragile X syndrome, and suggested that psychostimulant treatment may improve performance by acting on one or both… CONTINUE READING
54 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 54 extracted citations

Similar Papers

Loading similar papers…