Obituary—Ferdinando Rossi (1960–2014)

  title={Obituary—Ferdinando Rossi (1960–2014)},
  author={Timothy J. Ebner and Noriyuki Koibuchi and Mario Manto and Jean Mariani and On behalf of the Society for Research on the Cerebellum},
  journal={The Cerebellum},
Our community of researchers is saddened by the sudden death of Ferdinando Rossi. He passed away on January 24th, 2014. Ferdinando Rossi was born in Italy in 1960. From 1980 to 1983, he was trained at the Institute of Anatomy of the University of Turin. As an undergraduate student, he worked on plasticity of the neuromuscular junction using electron microscopy. He was particularly interested by cerebellar neurophysiology, synaptic plasticity, and the mechanisms of oculomotor control. He… 



Embryonic Purkinje Cells Grafted on the Surface of the Cerebellar Cortex Integrate in the Adult Unlesioned Cerebellum

Results show that embryonic Purkinje cells are able to survive and integrate in an adult unlesioned cerebellar cortex and adult olivary axons respond to the increased size of the target population by expanding their terminal domain to innervate grafted Purkinja cells.

Extracerebellar progenitors grafted to the neurogenic milieu of the postnatal rat cerebellum adapt to the host environment but fail to acquire cerebellar identities

Although exogenous cells are influenced by the cerebellar milieu and show remarkable capabilities for adapting to the foreign environment, they essentially fail to switch their fate, integrate in the host neurogenic mechanisms and adopt clear‐cut Cerebellar identities.

Origin, lineage and function of cerebellar glia

Lifespan of neurons is uncoupled from organismal lifespan

The lifespan of neurons is not limited by the maximum lifespan of the donor organism, but continues when transplanted in a longer-living host, like that of mice transplanted into the developing brain of Wistar rats.

Long-Term Injured Purkinje Cells Are Competent for Terminal Arbor Growth, but Remain Unable to Sustain Stem Axon Regeneration

The results indicate that the long-term injured Purkinje cells remain unable to activate the gene program required to sustain axon regeneration and their plasticity is restricted to terminal arbor remodeling.

Neurogenesis in the Cerebellum

  • B. CarlettiF. Rossi
  • Biology, Psychology
    The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry
  • 2008
The authors review cerebellar neurogenesis and discuss the fate mapping studies with other new information stemming from transplantation experiments, in an effort to link the developmental potential of neural progenitor populations of the cerebellum with their spatio-temporal origin.

Laminar Fate and Phenotype Specification of Cerebellar GABAergic Interneurons

In most CNS regions, the variety of inhibitory interneurons originates from separate pools of progenitors residing in discrete germinal domains, where they become committed to specific phenotypes and

Selective rather than inductive mechanisms favour specific replacement of Purkinje cells by embryonic cerebellar cells transplanted to the cerebellum of adult Purkinje cell degeneration (pcd) mutant mice

The very low mitotic rate of transplanted cells suggests that the adult cerebellum, either wild‐type or mutant, does not provide instructive neurogenic cues to direct the specification of uncommitted progenitors, and results indicate that some compensatory mechanisms operate in the pcd environment.

Specification and Differentiation of Cerebellar GABAergic Neurons

Cerebellar GABAergic projection neurons and interneurons originate from the ventricular neuroepithelium of the cerebellar primordium, but the two main classes of GABAergic neurons are generated according to distinct strategies.

Neurogenesis in the cerebellum. Neuroscientist

  • 2008