Obestatin improves memory performance and causes anxiolytic effects in rats.

@article{Carlini2007ObestatinIM,
  title={Obestatin improves memory performance and causes anxiolytic effects in rats.},
  author={Valeria Paola Carlini and Helgi B. Schi{\"o}th and Susana R Debarioglio},
  journal={Biochemical and biophysical research communications},
  year={2007},
  volume={352 4},
  pages={907-12}
}
Obestatin is a peptide hormone that is derived from the same polypeptide precursor (preprogrelin) as ghrelin, but it acts in opposing way on ingestive behavior. Our previous studies showed that ghrelin affects memory and anxiety. Here, we studied the possible effects of icv obestatin injection in rats upon memory retention (using two different paradigms), anxiety like behavior (plus maze test), and food intake. Obestatin induces an increase in the percentage of open arms entries (Obestatin 3… CONTINUE READING
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