Obesity in autoimmune diseases: not a passive bystander.

  title={Obesity in autoimmune diseases: not a passive bystander.},
  author={Mathilde Versini and P Y Jeandel and Eric Rosenthal and Yehuda Shoenfeld},
  journal={Autoimmunity reviews},
  volume={13 9},
In the last decades, autoimmune diseases have experienced a dramatic increase in Western countries. The involvement of environmental factors is strongly suspected to explain this rise. Particularly, over the same period, obesity has followed the same outbreak. Since the exciting discovery of the secretory properties of adipose tissue, the relationship between obesity and autoimmunity and the understanding of the underlying mechanisms have become of major interest. Indeed, the fat tissue has… CONTINUE READING