Obesity-associated genetic variants in young Asian Indians with the metabolic syndrome and myocardial infarction

@inproceedings{Ranjith2011ObesityassociatedGV,
  title={Obesity-associated genetic variants in young Asian Indians with the metabolic syndrome and myocardial infarction},
  author={Naresh Ranjith and Rosemary J. Pegoraro and Rebecca Shanmugam},
  booktitle={Cardiovascular journal of Africa},
  year={2011}
}
OBJECTIVE Associations between obesity-related polymorphisms and the metabolic syndrome in 485 young ( ≤ 45 Years) Asian Indian patients with acute myocardial infarction (AMI), and 300 matched controls were assessed. METHODS Genetic variants included the adiponectin 45T→G and 276G→T, LEPR K109R and Q223R, MC4R-associated C→T and FTO A→T polymorphisms. RESULTS The metabolic syndrome, as defined by NCEP ATP III and IDF criteria, was diagnosed in 61 and 60% of patients, respectively. No… CONTINUE READING

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Genome - wide association scan shows genetic variants in the FTO gene are associated with obesity - related traits . E - publication 26 th June 2009

  • TM Frayling, NJ Timpson, MN Weedon
  • PLoS Genet
  • 2009

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