Obesity-associated asthma in children: a distinct entity.

@article{Rastogi2012ObesityassociatedAI,
  title={Obesity-associated asthma in children: a distinct entity.},
  author={Deepa Rastogi and Stephen M. Canfield and Andrea Andrade and Carmen R. Isasi and Charles B. Hall and Arye Rubinstein and Raanan Arens},
  journal={Chest},
  year={2012},
  volume={141 4},
  pages={
          895-905
        }
}
BACKGROUND Obesity-associated asthma has been proposed to be a distinct entity, differing in immune pathogenesis from atopic asthma. Both obesity-mediated inflammation and increase in adiposity are potential mechanistic factors that are poorly defined among children. We hypothesized that pediatric obesity-associated asthma would be characterized by T helper (Th) 1, rather than the Th2 polarization associated with atopic asthma. Moreover, we speculated that Th1 biomarkers and anthropometric… 

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...

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