Obesity and the liver: nonalcoholic fatty liver disease.

  title={Obesity and the liver: nonalcoholic fatty liver disease.},
  author={Sean W.P. Koppe},
  journal={Translational research : the journal of laboratory and clinical medicine},
  volume={164 4},
The increasing prevalence of nonalcoholic fatty liver disease (NAFLD) parallels the rise of obesity and its complications. NAFLD is a common cause of cirrhosis and a leading indication for liver transplant. Genetic susceptibility, dietary composition, and exercise habits influence the development of NAFLD, and insulin resistance results in widespread metabolic perturbations with a net effect of triglyceride accumulation in the liver. Some patients will develop hepatocyte cellular injury and… CONTINUE READING
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