Obesity: New life for antidiabetic drugs

@article{Houtkooper2010ObesityNL,
  title={Obesity: New life for antidiabetic drugs},
  author={Riekelt H Houtkooper and Johan Auwerx},
  journal={Nature},
  year={2010},
  volume={466},
  pages={443-444}
}
Obesity and its associated disorders (diabetes, cancer and cardiovascular disease,among others) have reached epidemic proportions worldwide. Understanding the mechanisms of metabolic control in order to prevent and treat these metabolic disorders is therefore a top research priority. On page 451 of this issue, Spiegelman and colleagues (Choi et al.) make a significant contribution by showing that phosphorylation of one protein, PPARγ, plays a part in insulin resistance and obesity. The story of… CONTINUE READING
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