Obesity, metabolic syndrome, and airway disease: a bioenergetic problem?

  title={Obesity, metabolic syndrome, and airway disease: a bioenergetic problem?},
  author={Anurag Agrawal and Y S Prakash},
  journal={Immunology and allergy clinics of North America},
  volume={34 4},
Multiple studies have determined that obesity increases asthma risk or severity. Metabolic changes of obesity, such as diabetes or insulin resistance, are associated with asthma and poorer lung function. Insulin resistance is also found to increase asthma risk independent of body mass. Conversely, asthma is associated with abnormal glucose and lipid metabolism, insulin resistance, and obesity. Here we review our current understanding of how dietary and lifestyle factors lead to changes in… CONTINUE READING
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