Obesity, immunomodulation and chronic kidney disease.

@article{Brgeson2013ObesityIA,
  title={Obesity, immunomodulation and chronic kidney disease.},
  author={Emma B{\"o}rgeson and Kumar Sharma},
  journal={Current opinion in pharmacology},
  year={2013},
  volume={13 4},
  pages={
          618-24
        }
}
Obesity-induced inflammation is associated with numerous pathologies and is an independent risk factor of chronic kidney disease (CKD). The prevalence of CKD is escalating and current therapeutic strategies are seriously lacking in efficacy, and immunomodulation has been suggested as a potential new therapeutic approach. Indeed, specialized pro-resolving mediators (SPMs), such as lipoxins (LXs), resolvins and protectins, have demonstrated protection in adipose inflammation, restoring insulin… CONTINUE READING

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