Oat β-glucan: physico-chemical characteristics in relation to its blood-glucose and cholesterol-lowering properties
@article{Wang2014OatP, title={Oat $\beta$-glucan: physico-chemical characteristics in relation to its blood-glucose and cholesterol-lowering properties}, author={Qi Wang and Peter R. Ellis}, journal={British Journal of Nutrition}, year={2014}, volume={112}, pages={S4 - S13} }
The water-soluble, mixed-linkage β-glucan, a form of soluble dietary fibre, is considered the main biologically active component responsible for the capacity of many oat products to lower postprandial glycaemia and fasting plasma cholesterol in human subjects. The present review discusses the physical and chemical properties of oat β-glucan that are considered important predictors of these beneficial metabolic effects. In vitro modelling and animal and human studies have provided compelling…
107 Citations
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References
SHOWING 1-10 OF 101 REFERENCES
β-Glucan from Two Sources of Oat Concentrates Affect Postprandial Glycemia in Relation to the Level of Viscosity
- Chemistry, MedicineJournal of the American College of Nutrition
- 2007
This study shows that processing oat β-glucan through enzymatic, rather than by aqueous methods, preserves the viscosity and improves postprandial glycemic control.
Physicochemical properties of beta-glucan in differently processed oat foods influence glycemic response.
- Chemistry, MedicineJournal of agricultural and food chemistry
- 2009
Characterizing the physicochemical properties of beta-glucan in bioactive foods aids functional food development by identifying the highest efficacy in attenuating the peak blood glucose response (PBGR) and depolymerization in bread and pasta reduced beta-Glucan bioactivity.
Physicochemical properties of oat β-glucan influence its ability to reduce serum LDL cholesterol in humans: a randomized clinical trial.
- MedicineThe American journal of clinical nutrition
- 2010
The physicochemical properties of oat β-glucan should be considered when assessing the cholesterol-lowering ability of Oat-containing products; an extruded breakfast cereal containing 3 g oatβ- glucan/d with a high-MW or a medium-MW lowered LDL cholesterol similarly by 5%, but efficacy was reduced by 50% when MW was reduced to 210,000 g/mol.
Processing affects the physicochemical properties of beta-glucan in oat bran cereal.
- Chemistry, MedicineJournal of agricultural and food chemistry
- 2010
Microscopic examination showed that as the extrusion conditions were made more severe, to cause depolymerization, the integrity of the cell walls was lost and beta-glucan dispersed throughout the cereal and the apparent viscosity in the physiological extract dropped.
The molecular weight, solubility and viscosity of oat beta-glucan affect human glycemic response by modifying starch digestibility.
- Chemistry, MedicineFood chemistry
- 2011
Effects of environment and variety on content and molecular weight of β-glucan in oats
- Chemistry
- 2011
Molecular Weight Distribution of β-Glucan in Oat-Based Foods
- Chemistry
- 2004
ABSTRACT Oats, different oat fractions as well as experimental and commercial oat-based foods, were extracted with hot water containing thermostable α-amylase. Average molecular weight and molecular…
Interactional effects of β-glucan, starch, and protein in heated oat slurries on viscosity and in vitro bile acid binding.
- Chemistry, MedicineJournal of agricultural and food chemistry
- 2012
It is illustrated that β-glucan was the major contributor to viscosity and in vitro bile acid binding in heated oat slurries; however, interactions with other components, such as protein and starch, indicate the importance of evaluating oat components as whole system.
Reducing Beta-Glucan Solubility in Oat Bran Muffins by Freeze-Thaw Treatment Attenuates Its Hypoglycemic Effect
- Chemistry
- 2007
ABSTRACT The viscosity of soluble fibers such as β-glucan depends on their concentration in solution and molecular weight (MW) distribution. We investigated whether freezing treatment of oat bran…