OXA-372, a novel carbapenem-hydrolysing class D β-lactamase from a Citrobacter freundii isolated from a hospital wastewater plant.

@article{Antonelli2015OXA372AN,
  title={OXA-372, a novel carbapenem-hydrolysing class D β-lactamase from a Citrobacter freundii isolated from a hospital wastewater plant.},
  author={Alberto Antonelli and Marco Maria D'Andrea and Guendalina Vaggelli and J D Docquier and Gian Maria Rossolini},
  journal={The Journal of antimicrobial chemotherapy},
  year={2015},
  volume={70 10},
  pages={2749-56}
}
OBJECTIVES The objective of this study was to characterize a novel class D carbapenemase, named OXA-372, identified in a carbapenem-resistant Citrobacter freundii strain (Cfr-FI-07) isolated from a hospital wastewater plant in central Italy. METHODS Cfr-FI-07 was isolated using a selective chromogenic medium for carbapenem-resistant Enterobacteriaceae. Carbapenemase production was confirmed by spectrophotometric assay. WGS was carried out using an Illumina MiSeq platform. The functional… CONTINUE READING

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