OX40 is differentially expressed on activated rat and mouse T cells and is the sole receptor for the OX40 ligand.

@article{AlShamkhani1996OX40ID,
  title={OX40 is differentially expressed on activated rat and mouse T cells and is the sole receptor for the OX40 ligand.},
  author={Aymen Al-Shamkhani and Marian L Birkeland and Michael J. Puklavec and Marion H Brown and William James and A. Neil Barclay},
  journal={European journal of immunology},
  year={1996},
  volume={26 8},
  pages={1695-9}
}
OX40, a member of the tumor necrosis factor (TNF) receptor/nerve growth factor (NGF) receptor superfamily was first identified as a marker of activated rat CD4+ cells with the MRC OX40 monoclonal antibody (mAb). A ligand for OX40 (called OX40 ligand or OX40L) has recently been identified and has sequence similarity to TNF. Mouse OX40L-immunoglobulin fusion protein (OX40L-Ig) binds to activated mouse CD4+ and CD8+ cells (Baum, P. R. et al., EMBO J. 1994. 13: 3992) suggesting that OX40 could have… CONTINUE READING

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