OSCAR: One-class SVM for accurate recognition of cis-elements

@article{Jiang2007OSCAROS,
  title={OSCAR: One-class SVM for accurate recognition of cis-elements},
  author={Bo Jiang and Michael Q. Zhang and Xuegong Zhang},
  journal={Bioinformatics},
  year={2007},
  volume={23 21},
  pages={
          2823-8
        }
}
MOTIVATION Traditional methods to identify potential binding sites of known transcription factors still suffer from large number of false predictions. They mostly use sequence information in a position-specific manner and neglect other types of information hidden in the proximal promoter regions. Recent biological and computational researches, however, suggest that there exist not only locational preferences of binding, but also correlations between transcription factors. RESULTS In this… CONTINUE READING

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