OS006. Functional expression of endogenous ligands of Toll like receptor4 on monocytes and placentae from women during normal pregnancy andpre-eclampsia.

INTRODUCTION Preeclampsia (PE) is characterized by an exaggerated systemic inflammatory response (ESIR). Several recent studies by our group and others have demonstrated up-regulation of Toll like receptor 4 (TLR4) in trophoblast, placenta and leukocytes in PE but the exact role of TLR4 in the pathogenesis of PE remains unclear. OBJECTIVES We sought to… CONTINUE READING