ORAL VERSUS INTRAMUSCULAR VITAMIN A IN THE TREATMENT OF XEROPHTHALMIA

@article{Sommer1980ORALVI,
  title={ORAL VERSUS INTRAMUSCULAR VITAMIN A IN THE TREATMENT OF XEROPHTHALMIA},
  author={Alfred Sommer and Ignatius Tarwotio and Muhilal and Edi Djunaedi and J H Glover},
  journal={The Lancet},
  year={1980},
  volume={315},
  pages={557-559}
}

Protein deficiency and treatment of xerophthalmia.

In a controlled clinical trial of massive-dose vitamin A therapy for xerophthalmia, holo-retinol-binding protein (holo-RBP) response was related to baseline protein status and Correction of PEM is essential to ensuring a sustained clinical cure.

Vitamin A treatment for herpes keratitis.

  • A. Sommer
  • Medicine
    Archives of ophthalmology
  • 1980
The report by Smolin et al on the beneficial effect of vitamin A in herpes keratitis in (presumably nondeficient) rabbits is intriguing, but their suggestion that the same dose extrapolated to humans "would probably not be toxic" is in error.

Xerophthalmia, keratomalacia and nutritional blindness

  • A. Sommer
  • Medicine
    International Ophthalmology
  • 2004
Oral administration of high dose supplements, vitamin A fortification of commonly consumed items, or increased dietary intake of natural sources of vitamin A will reduce the number of needlessly blind young children.

Early serum changes in severely malnourished children with corneal xerophthalmia after injection of water-miscible vitamin A.

In no group did retinol-binding protein or prealbumin reach normal levels 24 h after dose, and eye recovery and weight gain was so good after 50,000 IU as after higher doses.

Acute sixth nerve palsy in vitamin A treatment of xerophthalmia

A case of acute sixth nerve palsy in an infant receiving intramuscular vitamin A for xerophthalmia secondary to cystic fibrosis is reported.

Vitamin A deficiency and xerophthalmia.

  • A. Sommer
  • Medicine
    Archives of ophthalmology
  • 1990
The mechanism(s) by which vitamin A deficiency results in corneal ulceration and necrosis remains uncertain, but local sepsis appears to be a late and variable complication.

Absorption of vitamin A by children with diarrhoea during treatment with oral rehydration salt solution.

It is indicated that absorption is lower in children with acute diarrhoea compared with normal children and the glucose or electrolytes present in solutions of oral rehydration salts had no effect on the absorption.

Xerophthalmia and vitamin a status

  • A. Sommer
  • Medicine
    Progress in Retinal and Eye Research
  • 1998

[Vitamin A deficiency and xerophtalmia]

There is evidence of vitamin A deficiency among Brazilian children and it is of paramount importance that vitamin A be included in public policy plans so that the authors can ensure the survival of children.
...

References

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