The efficacy of bone marrow
- N Yalman, E Sepet, G Aren, Z Mete, G Kulekci, S. Anak
- Clin. Pesq. Odontol., Curitiba, v.2,
Objective: The objective of this study was to evaluate the oral and dermatologic findings in a group of patients with Fanconi ́s anemia. Patients and Method: 30 pacients with Fanconi ́s anemia under treatment at the Clinics Hospital of the Federal University of Paraná and at the Associação Paranaense de Apoio à Criança com Neoplasia em Curitiba, PR, Brazil were evaluated. The research was an exploratory type study and the focus was in the oral mucosa and in the skin were clinically evaluated. Patients submitted to bone marrow transplantation were excluded from this study. Results: 18 patients were female and 12 male; mean age 10 years and 10 month. The dermatological findings were present in 68% of the patients. (p< 0.05) (t test) (skin pigmentation, cafe-au-lait spots, petecchia and purpure). Melanine pigmentation, hypochromatic areas, nodules, spots and gingivitis were found in the oral mucosa of all patients (100 %). Conclusion: There is a high prevalence of oral and head and neck dermatological and oral alterations in patients with Fanconi ́s anaemia.