OPTIMIZATION OF DIRECT COMPRESSION TABLET FORMULATIONS FOR USE IN TROPICAL COUNTRIES

@article{Bos1991OPTIMIZATIONOD,
  title={OPTIMIZATION OF DIRECT COMPRESSION TABLET FORMULATIONS FOR USE IN TROPICAL COUNTRIES},
  author={C. E. Bos and G. K. Bolhuis and Coenraad F. Lerk and Jan Hendrik de Boer and C. A. A. Duineveld and Age K. Smilde and D. A. Doornbos},
  journal={Drug Development and Industrial Pharmacy},
  year={1991},
  volume={17},
  pages={2477-2496}
}
AbstractWith the aid of a combined mixture- and factorial- design, 2 standard tablet formulations were selected suitable for use in tropical countries. The formulations were based on native ingredients or ingredients that are available worldwide. The selection of the standard formulations was based on both the initial tablet properties of the formulations one day after preparation as well as the physical stability after storage under tropical conditions.The selected formulations were evaluated… 
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