OPERA-LG: efficient and exact scaffolding of large, repeat-rich eukaryotic genomes with performance guarantees

@inproceedings{Gao2016OPERALGEA,
  title={OPERA-LG: efficient and exact scaffolding of large, repeat-rich eukaryotic genomes with performance guarantees},
  author={Song Gao and Denis Bertrand and Burton Chia and Niranjan Nagarajan},
  booktitle={Genome Biology},
  year={2016}
}
The assembly of large, repeat-rich eukaryotic genomes represents a significant challenge in genomics. While long-read technologies have made the high-quality assembly of small, microbial genomes increasingly feasible, data generation can be expensive for larger genomes. OPERA-LG is a scalable, exact algorithm for the scaffold assembly of large, repeat-rich genomes, out-performing state-of-the-art programs for scaffold correctness and contiguity. It provides a rigorous framework for scaffolding… CONTINUE READING

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