OPCML gene promoter methylation and gene expression in tumor and stroma cells of invasive cervical carcinoma.

Abstract

To investigate the CpG island methylation and the mRNA expression of OPCML gene in patients with cervical carcinoma, we collected tumor and stroma cells from 36 invasive cervical carcinoma samples and 16 normal cervical tissues as well as Hela cells. Methylation specific PCR was used to detect promoter CpG island methylation status, and fluorescence… (More)
DOI: 10.1080/07357900701837044

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