ON BEING THE RIGHT SIZE: HEART DESIGN, MITOCHONDRIAL EFFICIENCY and LIFESPAN POTENTIAL

@article{Dobson2003ONBT,
  title={ON BEING THE RIGHT SIZE: HEART DESIGN, MITOCHONDRIAL EFFICIENCY and LIFESPAN POTENTIAL},
  author={Geoffrey P. Dobson},
  journal={Clinical and Experimental Pharmacology and Physiology},
  year={2003},
  volume={30}
}
  • G. Dobson
  • Published 1 August 2003
  • Biology, Medicine
  • Clinical and Experimental Pharmacology and Physiology
1. From the smallest shrew or bumble‐bee bat to the largest blue whale, heart size varies by over seven orders of magnitude (from 12 mg to 600 kg). This study reviews the scaling relationships between heart design, cellular bioenergetics and mitochondrial efficiencies in mammals of different body sizes. 
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  • Medicine, Biology
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Small animal model species are not created equal.
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