OEIS complex (omphalocele-exstrophy-imperforate anus-spinal defects) in monozygotic twins.

  title={OEIS complex (omphalocele-exstrophy-imperforate anus-spinal defects) in monozygotic twins.},
  author={D H Lee and John R. Cottrell and Reginald C. Sanders and Cynthia R. Meyers and Eric A. Wulfsberg and Charlotte C. Sun},
  journal={American journal of medical genetics},
  volume={84 1},
The omphalocele-exstrophy-imperforate anus-spinal defects (OEIS) complex is a consistent and recognizable pattern of midline abdominal and pelvic defects. It is rare, affecting 1 in 200,000 to 400,000 pregnancies and is even rarer in twin gestations. This is an autopsy study of OEIS complex in monozygotic twins after pregnancy termination at 20 weeks of gestation. Unremarkable family history but concordance of monozygotic twins for the defects may support the theory that early malformation… CONTINUE READING


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