OCTOPUS: improving topology prediction by two-track ANN-based preference scores and an extended topological grammar

@article{Viklund2008OCTOPUSIT,
  title={OCTOPUS: improving topology prediction by two-track ANN-based preference scores and an extended topological grammar},
  author={H{\aa}kan Viklund and Arne Elofsson},
  journal={Bioinformatics},
  year={2008},
  volume={24 15},
  pages={1662-8}
}
MOTIVATION As alpha-helical transmembrane proteins constitute roughly 25% of a typical genome and are vital parts of many essential biological processes, structural knowledge of these proteins is necessary for increasing our understanding of such processes. Because structural knowledge of transmembrane proteins is difficult to attain experimentally, improved methods for prediction of structural features of these proteins are important. RESULTS OCTOPUS, a new method for predicting… CONTINUE READING
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