O o mutations in the galactose operon in E. coli


Eleven mutants lacking the three enzymes of galactose fermentation were investigated. Eight of the mutants revert spontaneously to the Gal + phenotype. These cannot be deletions. Six of these spontaneously reverting mutants do not respond to the mutagens 2-aminopurine, ethyl-methanesulfonate and N-Methyl-N′-Nitro-N-nitrosoguanidine. It is concluded that… (More)
DOI: 10.1007/BF00333604