O-GlcNAcylation of MLL5β is essential for MLL5β-AP-1 transcription complex assembly at the HPV16/18-long control region.

@article{Nin2015OGlcNAcylationOM,
  title={O-GlcNAcylation of MLL5β is essential for MLL5β-AP-1 transcription complex assembly at the HPV16/18-long control region.},
  author={Dawn Sijin Nin and Weitai Huang and Muzaffar Ali and Chow Wenn Yew and Tatiana G Kutateladze and Lih-Wen Deng},
  journal={Journal of molecular cell biology},
  year={2015},
  volume={7 2},
  pages={
          180-3
        }
}
Dear Editor, Cervical cancer is one of the leading causes of cancer death in women (Munoz et al., 2004), and current treatment strategies though effective still possess limitations. Thus, identification of more molecular-targeted therapeutics for cervical cancer is urgently needed. We recently identified an isoform of mixed lineage leukemia 5 (MLL5b, 503 amino acids) that is specifically expressed in HPV16/ 18+ cervical cancer cell lines and patient samples (Yew et al., 2011). MLL5b was found… CONTINUE READING
BETA

References

Publications referenced by this paper.
SHOWING 1-10 OF 12 REFERENCES

A peptide panel investigation reveals the acceptor specificity of O-GlcNAc transferase.

  • FASEB journal : official publication of the Federation of American Societies for Experimental Biology
  • 2014
VIEW 1 EXCERPT

efficiently kills human papillomavirus - positive cancer cells

R. Deplus, B. Delatte, M. Schwinn
  • Oncogene
  • 2013
VIEW 1 EXCERPT

siRNA targeting of the viral E 6

K. Butz, T. Ristriani, A. Hengstermann
  • oncogene
  • 2003
VIEW 1 EXCERPT

Similar Papers

Loading similar papers…