Nutritionally induced adipose hypertrophy in young pigs is transient and independent of changes in the expression of the obese and peroxisome proliferator activated receptor genes.

@article{Spurlock2002NutritionallyIA,
  title={Nutritionally induced adipose hypertrophy in young pigs is transient and independent of changes in the expression of the obese and peroxisome proliferator activated receptor genes.},
  author={Michael E. Spurlock and Christopher A. Bidwell and Karen L Houseknecht and Joanne L Kuske and Carmen Camacho-Rea and Gert Frank and Gawain M. Willis},
  journal={The Journal of nutritional biochemistry},
  year={2002},
  volume={13 2},
  pages={
          112-120
        }
}
Previous studies have shown that piglets weaned to a liquid milk replacer (MR), rather than a typical dry diet (DD) regimen, have improved growth rates and deposit more energy as body fat. In the present study, we used this model to determine whether changes in the expression of genes linked to the regulation of adiposity were related to the accelerated fat accretion. We also determined whether the increase in body fat was sustained throughout a substantial proportion of the growth curve. At… CONTINUE READING