• Corpus ID: 19902830

Nutritional supplements in depressive disorders.

@article{MartnezCengotitabengoa2017NutritionalSI,
  title={Nutritional supplements in depressive disorders.},
  author={M{\'o}nica Mart{\'i}nez‐Cengotitabengoa and Ana M Gonz{\'a}lez-Pinto},
  journal={Actas espanolas de psiquiatria},
  year={2017},
  volume={45 Supplement},
  pages={
          8-15
        }
}
There is increasing evidence about the role of nutrients in mental health. An adequate intake of nutrients contributes to better overall health and mental health in particular. Major depression is a severe mental illness with a high prevalence for which effective treatments exist but not in all cases the patient’s remission is achieved. Therefore, it is increasingly aimed at optimizing the supply of nutrients necessary for adequate brain functioning as adjunctive therapy to antidepressant… 
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22 Citations
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Background Citations
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Methods Citations
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22 Citations

The Role of Supplements in Treatment of Depression

This review explores studies regarding the role of different nutrients in treatment of depression and found Testosterone, Omega 3 fatty acid, Thyroid hormones, Modafinil, Folate, Vitamin B12, S-Adenosyl Methionine, Magnesium, and Zinc as supplements which has some effect in combination with anti-depressant medications.

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Emerging Role of Flavonoids as the Treatment of Depression

This review is an attempt to analyze pre-clinical studies, structural activity relationship and characteristics of reported isolated flavonoids, which may be considered for clinical trials for the development of therapeutically useful antidepressant.

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The results of this study may contribute to a better understanding of the recommended dietary antioxidant intake as an adjuvant for preventing depression in women.

Vitamin B12 and Folic Acid in Depression and Anxiety: A Pilot Study

Serum levels of vitamin B12 and folic acid could be used as markers that assess anxiety and depression's therapeutic efficiency and there was a significant inverse correlation between folic Acid levels and Beck's inventory score among patients with severe depression.

Zinc in depression: From development to treatment: A comparative/ dose response meta-analysis of observational studies and randomized controlled trials.

79 References

Nutritional medicine as mainstream in psychiatry.

International Society for Nutritional Psychiatry Research consensus position statement: nutritional medicine in modern psychiatry

  • J. SarrisA. Logan F. Jacka
  • Medicine, Psychology
    World psychiatry : official journal of the World Psychiatric Association
  • 2015
It is advocated that evidence-based nutritional change should be regarded as an efficacious and cost-effective means to improve mental health, and that nutrient-based (nutraceutical) prescription has the potential to assist in the management of mental disorders at the individual and population level.

Dietary recommendations for the prevention of depression

It is imperative to remain mindful of any protective effects that are likely to come from the cumulative and synergic effect of nutrients that comprise the whole-diet, rather than from the effects of individual nutrients or single foods.

Effect of zinc supplementation on antidepressant therapy in unipolar depression: a preliminary placebo-controlled study.

This preliminary study is the first demonstration of the benefit of zinc supplementation in antidepressant therapy and the mechanism(s) may be related to modulation of glutamatergic or immune systems by zinc ion.

Omega 3 polyunsaturated fatty acids and the treatment of depression

The role of omega 3 polyunsaturated fatty acids (n-3 PUFA) as a possible treatment for depression is explored and increasing evidence from epidemiological, laboratory, and randomized placebo-controlled trials suggests deficiency of dietary n- 3 PUFAs may contribute to development of mood disorders, and supplementation with n-3FUFA may provide a new treatment option.

Effects of Zinc Supplementation in Patients with Major Depression: A Randomized Clinical Trial

The results of the present study indicate that zinc supplementation together with SSRIs antidepressant drug improves major depressive disorders more effectively in patients with placebo plus antidepressants (SSRIs).

Folate in depression: efficacy, safety, differences in formulations, and clinical issues.

Several forms of folate appear to be safe and efficacious in some individuals with major depressive disorder, but more information is needed about dosage and populations most suited to folate therapy.

Omega-3 fatty acids in psychiatry.

S-Adenosyl Methionine (SAMe) for Depression in Adults

  • Amanda Wilson
  • Psychology, Medicine
    Issues in mental health nursing
  • 2019
The mechanism for the antidepressant effect of SAMe is unclear, however there is some evidence that it is effective in the treatment of depression, and to recommend this as an alternative to current treatments, the need to able to provide comparative risks, benefits and costs.

Folate and unipolar depression.

Depressed patients with both low and normal folate levels may benefit from augmenting a primary antidepressant medication either initially, at the onset of treatment, or later after some degree of treatment resistance has been recognized.
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