Nutritional supplementation with Chlorella pyrenoidosa for mild to moderate hypertension.

@article{Merchant2002NutritionalSW,
  title={Nutritional supplementation with Chlorella pyrenoidosa for mild to moderate hypertension.},
  author={Randall E. Merchant and Cynthia A. Andre and Domenic A. Sica},
  journal={Journal of medicinal food},
  year={2002},
  volume={5 3},
  pages={
          141-52
        }
}
Pharmacological treatment of hypertension reduces the risk of cardiovascular disease; however, randomized, controlled clinical trials and population studies have also shown that abnormally high blood pressure (BP) can be lowered with diet modification and exercise. The objective of this pilot study was to determine whether daily dietary supplementation with 10 g Chlorella tablets and 100 ml Chlorella extract for 2 months would reduce BP in subjects with a mean sitting diastolic BP (SiDBP… Expand
Effect of Chlorella supplementation on cardiovascular risk factors: A meta-analysis of randomized controlled trials.
TLDR
Subgroup analyses revealed that administration of Chlorella for 8 weeks or higher and doses higher than 4 g/day significantly reduced TC, LDL-C, SBP, and DBP levels in the participants, and also reduced SBP andDBP in hypertensive ones. Expand
Chlorella pyrenoidosa ameliorated L-NAME-induced hypertension and cardiorenal remodeling in rats
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TLDR
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Impact of Chlorella pyrenoidosa on the attenuation of hyperglycemia-mediated oxidative stress and protection of kidney tissue in streptozotocin-cadmium induced diabetic nephropathic rats
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The results of the present study implies that C. pyrenoidosa at a dose of 100 mg/ kg bodyweight exhibit more potential hypoglycemic and renoprotective properties than the other two tested doses. Expand
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TLDR
Chlorella supplementation to mammals, including humans, has been reported to exhibit various pharmacological activities, including immunomodulatory, antioxidant, antidiabetic, antihypertensive, and antihyperlipidemic activities. Expand
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TLDR
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TLDR
Although statistically significant alterations were noted in several parameters among males and females, these changes were deemed to be of no toxicological significance due to the lack of dose-response relationships, the fact that they occurred in only one sex, and the absence of any supporting gross or microscopic alterations. Expand
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TLDR
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