Nutritional regulation of coupling factor 6, a novel vasoactive and proatherogenic peptide.


High sodium, high glucose, and obesity are important risk factors for age-related diseases such as cardiovascular disease (CVDs), stroke, and cancer. Coupling factor 6 (CF6) is released from vascular endothelial cells and functions as a circulating peptide that inhibits prostacyclin and nitric oxide generation by intracellular acidosis. High glucose… (More)
DOI: 10.1016/j.nut.2016.07.017


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