Nutritional programming of accelerated puberty in heifers: alterations in DNA methylation in the arcuate nucleus.

@article{Alves2017NutritionalPO,
  title={Nutritional programming of accelerated puberty in heifers: alterations in DNA methylation in the arcuate nucleus.},
  author={Bruna R. C. Alves and Rodolfo Cardoso and Ryan Doan and Youwen Zhang and Scott V Dindot and Gary L. Williams and Marcel Amstalden},
  journal={Biology of reproduction},
  year={2017},
  volume={96 1},
  pages={174-184}
}
High rates of body weight gain during the juvenile period appear to program molecular events within the hypothalamus, leading to advancement of puberty. Methylation of DNA, an epigenetic mechanism that controls gene expression, is associated with metabolic programming events and is proposed to play a role in the pubertal process. In this study, DNA… CONTINUE READING