Nutritional aspects of manganese from experimental studies.

  title={Nutritional aspects of manganese from experimental studies.},
  author={Carl L. Keen and Jodi L. Ensunsa and Mark H. Watson and Deborah L. Baly and Sharon M Donovan and Marcia H. Monaco and Michael S. Clegg},
  volume={20 2-3},
In experimental animals, dietary manganese deficiency can result in numerous biochemical and structural abnormalities. Deficient animals can be characterized by impaired insulin production, alterations in lipoprotein metabolism, an impaired oxidant defense system, and perturbations in growth factor metabolism. If the deficiency occurs during early development, there can be pronounced skeletal abnormalities and an irreversible ataxia. Several lines of evidence suggest that manganese deficiency… CONTINUE READING
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