Nutritional Infertility: The Role of the Interconnected Hypothalamic Neuropeptide Y–Galanin–Opioid Network

  title={Nutritional Infertility: The Role of the Interconnected Hypothalamic Neuropeptide Y–Galanin–Opioid Network},
  author={Satya P. Kalra and Pushpa S. Kalra},
  journal={Frontiers in Neuroendocrinology},
  • S. Kalra, P. Kalra
  • Published 1 October 1996
  • Biology
  • Frontiers in Neuroendocrinology
Neuropeptide Y (NPY) has been implicated in the hypothalamic regulation of reproduction and energy homeostasis. The perikarya located primarily in the arcuate nucleus (ARC) of the hypothalamus constitute a common source of NPY. Projections from these neurons along two distinct pathways, namely, the reproductive axis of the ARC--median eminence--medial preoptic area and the orexigenic axis of the ARC--paraventricular nucleus and neighboring regions, participate in regulation of these two… 
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Neuroendocrine Interactions between Galanin, Opioids, and Neuropeptide Y in the Control of Reproduction and Appetite a
Galanin is a pleiotropic neuroendocrine signal produced in discrete subpopulations of neurons distributed in several sites in the hypothalamus, and an interconnected network composed of these three neuropeptide‐producing neurons provides precision and site specificity in the relay of information necessary to govern reproduction and appetite.
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  • Biology
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