Nutritional Control of Reproductive Status in Honeybees via DNA Methylation

@article{Kucharski2008NutritionalCO,
  title={Nutritional Control of Reproductive Status in Honeybees via DNA Methylation},
  author={Robert Kucharski and Joanna Maleszka and Sylvain For{\^e}t and Ryszard Maleszka},
  journal={Science},
  year={2008},
  volume={319},
  pages={1827 - 1830}
}
Fertile queens and sterile workers are alternative forms of the adult female honeybee that develop from genetically identical larvae following differential feeding with royal jelly. [] Key Result We show that silencing the expression of DNA methyltransferase Dnmt3, a key driver of epigenetic global reprogramming, in newly hatched larvae led to a royal jelly-like effect on the larval developmental trajectory; the majority of Dnmt3 small interfering RNA-treated individuals emerged as queens with fully…
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